Spicule Retinol PDRN Cream 15gr

THE Spicule Retinol PDRN Cream Mary & May's is a highly advanced anti-aging treatment that combines Retinol high performance, Low molecular weight CICA-PDRN and Natural Micro-Spicules (2,000 shots) for deep renewal, smoothing and visible improvement in skin firmness.

The micro-spicules, natural micro-needles from sea sponges, create tiny penetration “channels” that enhance the absorption of Retinol and PDRN, multiplying their effectiveness. This technology mimics a gentle microneedling, activating natural mechanisms of skin regeneration and strengthening.

The nano-liposomal Retinol smoothes wrinkles and fine lines, offering smoother, brighter and renewed skin, while the CICA-PDRN It contributes to regeneration, reduces irritation and enhances elasticity. The result is a skin that is fuller, firmer and visibly lifted.

The texture of the cream is concentrated, but spreads evenly without being heavy, ideal as a targeted anti-aging care on cheekbones, nasolabial folds, forehead and areas with relaxation.

✔ Micro-Spicules (2,000 shots)
They enhance absorption and activate regeneration (microneedling effect).

✔ Nano-Liposomal Retinol
Strong but consistent smoothing action without irritation.

✔ CICA-PDRN (low molecular weight)
Barrier strengthening • regeneration • reduction of irritation.

✔ Panthenol 2%
Soothing & protection after the action of spicules.

✔ Pore & texture improvement
Smoother, more even skin with long-term use.

✔ Ideal for targeted anti-aging
Areas of relaxation, expression wrinkles, tired appearance.

Active Ingredients:

Natural Micro-Spicules → create deep absorption pathways

Retinol (Nano-Liposomal) → wrinkle smoothing, cell renewal

CICA-PDRN → regeneration, healing & barrier strengthening

Panthenol 2% → comfort & protection

Centella Asiatica Extract → calms and reduces redness

Allantoin → soothing & relieving effect

Hyaluronic Acid → hydration & plumping

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How to Use:

Apply a very small amount to clean skin only. night. Apply to targeted areas: cheekbones, nasolabial folds, forehead, expression lines. Massage lightly to activate the micro-spicules. Allow to absorb completely and follow with moisturizer. Use 2–3 times a week at first and increase gradually. On the day everything sunscreen.

You may feel a mild “micro-tingling” sensation — this is normal and indicates the action of the spicules.

Fits: Skin with sagging & reduced elasticity // Wrinkles, expression lines and a tired look // Uneven texture & pores // Those who want a result like mild microneedling // Mature and photoaged skin.